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Cocaine Publications

• Cooper ZD, Narasimhan D, Sunahara RK, Mierzejewski P, Jutkiewicz EM, Larsen NA, Wilson IA, Landry DW, Woods JH. Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Mol Pharmacol. 2006 Dec;70(6):1885-91. Epub 2006 Sep 12.
• Zhan CG, Deng SX, Skiba JG, Hayes BA, Tschampel SM, Shields GC, Landry DW. First-principle studies of intermolecular and intramolecular catalysis of protonated cocaine. J Comput Chem. 2005 Jul 30;26(10):980-6.
• Larsen NA, de Prada P, Deng SX, Mittal A, Braskett M, Zhu X, Wilson IA, Landry DW. Crystallographic and biochemical analysis of cocaine-degrading antibody 15A10. Biochemistry. 2004 Jun 29;43(25):8067-76.
• de Prada P, Landry DW. Production and characterization of anti-cocaine catalytic antibodies. Methods Mol Biol. 2004;248:495-501.
• Deng S, Bharat N, de Prada P, Landry DW. Substrate-assisted antibody catalysis. Org Biomol Chem. 2004 Feb 7;2(3):288-90. Epub 2003 Dec 24.
• Stojanović MN, Green EG, Semova S, Nikić DB, Landry DW. Cross-reactive arrays based on three-way junctions. J Am Chem Soc. 2003 May 21;125(20):6085-9.
• Zhan CG, Zheng F, Landry DW. Fundamental reaction mechanism for cocaine hydrolysis in human butyrylcholinesterase. J Am Chem Soc. 2003 Mar 5;125(9):2462-74.
• Larsen NA, Heine A, de Prada P, Redwan el-R, Yeates TO, Landry DW, Wilson IA. Structure determination of a cocaine hydrolytic antibody from a pseudomerohedrally twinned crystal. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2055-9. Epub 2002 Nov 23.
• Deng SX, de Prada P, Landry DW. Anticocaine catalytic antibodies. J Immunol Methods. 2002 Nov 1;269(1-2):299-310.
• Stojanovic MN, Landry DW. Aptamer-based colorimetric probe for cocaine. J Am Chem Soc. 2002 Aug 21;124(33):9678-9.
• Deng SX, Bharat N, Fischman MC, Landry DW. Covalent modification of proteins by cocaine. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3412-6. Epub 2002 Mar 12.
• Stojanovic MN, de Prada P, Landry DW. Aptamer-based folding fluorescent sensor for cocaine. J Am Chem Soc. 2001 May 30;123(21):4928-31.
• Briscoe RJ, Jeanville PM, Cabrera C, Baird TJ, Woods JH, Landry DW. A catalytic antibody against cocaine attenuates cocaine's cardiovascular effects  in mice: a dose and time course analysis. Int Immunopharmacol. 2001 Jun;1(6):1189-98.
• Kuhar MJ, Carroll FI, Bharat N, Landry DW. Anticocaine catalytic antibodies have no affinity for RTI compounds: implications for treatment. Synapse. 2001 Aug;41(2):176-8.
• Koetzner L, Deng S, Sumpter TL, Weisslitz M, Abner RT, Landry DW, Woods JH. Titer-dependent antagonism of cocaine following active immunization in rhesus monkeys. J Pharmacol Exp Ther. 2001 Mar;296(3):789-96.
• Baird TJ, Deng SX, Landry DW, Winger G, Woods JH. Natural and artificial enzymes against cocaine. I. Monoclonal antibody 15A10 and  the reinforcing effects of cocaine in rats. J Pharmacol Exp Ther. 2000 Dec;295(3):1127-34.
• De Prada P, Winger G, Landry DW. Application of artificial enzymes to the problem of cocaine. Ann N Y Acad Sci. 2000;909:159-69.
• Mets B, Winger G, Cabrera C, Seo S, Jamdar S, Yang G, Zhao K, Briscoe RJ, Almonte R, Woods JH, Landry DW. A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10176-81.
• Landry DW. Immunotherapy for cocaine addiction. Sci Am. 1997 Feb;276(2):42-5.
• Landry DW, Yang GX. Anti-cocaine catalytic antibodies--a novel approach to the problem of addiction. J Addict Dis. 1997;16(3):1-17.
• Landry DW, Zhao K, Yang GX, Glickman M, Georgiadis TM. Antibody-catalyzed degradation of cocaine. Science. 1993 Mar 26;259(5103):1899-901.
  
  

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