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Gangli Gong
Associate Research Scientist
650 W168th St, BB1029, New York, NY 10032
Phone: (212)305-1152
Fax: (212)305-3475
Email: gg2269@columbia.edu

Academic Qualification

PhD

Education

• University of Illinois at Chicago, Ph.D. Organic Chemistry
• Nanjing University, Nanjing, China, M.E. Applied Chemistry
• Nanjing University, Nanjing, China, B.S. Applied Chemistry

Training

• 2005-2006 Purdue University Postdoctoral Research Associate Total synthesis of (-)-lasonolide A; Synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease (SARS-3CLpro) inhibitors.
• 2000-2005  University of Illinois at Chicago Research Assistant Total syntheses of natural products, including: synthesis of C17-C28 fragment of laulimalide, enantioselective first total syntheis of (+)-amphidinolide W and revision of its C6 absolute stereochemistry, efforts toward total synthesis of (-)-lasonolide A (C3-C14 and C18-C41segments).
  Teaching Assistant  Teaching of undergraduate organic chemistry and lab.
• 1997-2000 Nanjing University Research Assistant Study of new process and absorbent for the carbon dioxide removal and regeneration.

Research Interests

• Total synthesis of natural products.
• Synthesis of biologically active small molecules.

Publications

• Ghosh, Arun K.; Gong, Gangli. Total Synthesis and Structural Revision of (+)-Amphidinolide W.  J. Am. Chem. Soc. 2004, 126, 3704 –3705.
• Ghosh, Arun K.; Gong, Gangli. Total Synthesis and Revision of C6 Stereochemistry of (+)-Amphidinolide W. J. Org. Chem. 2006, 71, 1085-1093.
• Ghosh, Arun K.; Gong, Gangli. Enantioselective Total Synthesis of Macrolide Antitumor Agent (-)-Lasonolide A. Org. Lett. 2007, 9, 1437-1440.
• Ghosh, Arun K.; Gong, Gangli. Total Synthesis of Potent Antitumor Agent (-)-Lasonolide A: a Cycloaddition-based Strategy Org. Biomol. Chem. 2008, submitted.
• Xie, Yuli; Deng, ShiXian; Thomas, Craig J.; Liu, Yidong; Zhang, Ya-Qin; Rinderspacher, Alison; Huang, Wenwei; Gong, Gangli; Wyler, Michael; Cayanis, Efithia; Aulner, Nathalie; Toebben, Udo; Chung, Caty; Pampou, Sergey; Southall, Noel; Vidovic, Dusica; Schuerer, Stephan; Branden, Lars; Davis, R. Eric; Staudt, Louis M.; Inglese, James; Austin, Christopher P.; Landry, Donald W.; Smith, Deborah H.; Auld, Douglas S.   Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFκB activity within two separate high-throughput screens of NFκB activation. Bioorg. & Med. Chem. Lett.  2008, 18,  329-335.
• Xie, Yuli; Gong, Gangli; Liu, Yidong; Deng, Shixian; Rinderspacher, Alison; Branden, Lars; Landry, Donald W. Convenient Preparation of N-8-quinolinyl Benzenesultams as Novel NF-κB Inhibitors. Tetrahedron Lett. 2008, in press.
• Gong, Gangli; Wang, Xiangyun; Zhang, Zhibing.  Solubilities of CO2 in biomimetic and other absorbents. Huagong Xuebao (Chinese Edition) 2001, 52, 349-353.
• Wang, Xiangyun; Gong, Gangli; Wang, Anrong; Hao, Aixiang; Wang, Zhihe. New process for pressure swing regeneration with low heat supply. Huafei Gongye (Chinese Edition) 2000, 27, 16-19.
  
  
  

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